Agricultural and Biosystems Engineering
Jacek Koziel, Associate Professor Department of Agricultural and Biosystems Engineering
Research interests: Quantification of emissions of volatile organic compounds, odor, NH3, H2S, and particulate matter from livestock operations, chemical and sensory analysis of odors from confined animal feeding operations using solid phase microextraction, multidimensional gas chromatography, mass spectromety, and olfactometry (SPME, GC, MS, O); development and testing of odor control technologies; environmental analysis; biotechnology; plant-aphid-insect interactions, human breath and oral malodor, polyphenolic compounds in grapes and wines.
Jeff Wolt, Professor, Biosafety Institute for Genetically Modified Agricultural Products, Agronomy
Risk analysis for new technologies in agriculture with emphasis on plant biotechnology. Applied soil solution chemistry as it pertains to plant nutrition and environmental fate of xenobiotics and transgenic protein.
Aileen Keating , Assistant Professor and Director of Graduate Education for Toxicology, Department of Animal Science
Reproductive physiology. My research focuses on how environmental chemicals affect ovarian physiology and function. Specifically, (1) investigating the mechanisms by which ovotoxic chemicals destroy follicles, (2) examining how the ovary metabolizes these chemicals, and (3) identifying therapeutic approaches to protect the ovary from such exposures.
Stephan Schmitz-Esser, Associate Professor, Department of Animal Science
Metagenomics. Area of interest is the interaction of eukaryotes and bacteria. These interactions have spanned model eukaryote and bacterial symbiont systems to microbiomes of farm animals. For understanding the genetic mechanisms underlying these interactions, genetics and genomics are key technologies I am using in my laboratory. We use various sequencing approaches as a hypothesis-generating tools and apply a variety of molecular genetics and molecular microbiological approaches to test these hypotheses.
Biochemistry, Biophysics and Molecular Biology
Marit Nilsen-Hamilton, Professor, American Association for the Advancement of Science (AAAS) Fellow, Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology
Regulation of gene expression by growth factors in animal cells, Imaging of gene expression in vivo, Applications of aptamers to medical technology
Vellareddy Anantharam, Adjunct Assistant Professor, Biomedical Sciences
Dr. Anantharam's research centers around the cellular and molecular mechanisms of neurodegeneration and neuroprotection and the application of such information to the development of novel strategies for treating several neurological disorders.
Chandrashekhar (Chandru) Charavaryamath, Assistant Professor, Biomedical Sciences. Focussed on understanding swine barn workers lung inflammation (using animal models). Occupational toxicology/inhalational toxicology and bacterial toxin research. Website at ISU in development but you can look here for previous insitutional information:
Michael Cho, Professor and Lloyd Chair in Biomedical Sciences, Co-Director, Center for Advanced Host Defense, Immunobiotics and Traslational Comparative Medicine (CAHDIT), Department of Biomedical Sciences
The primary focus of my laboratory is development of a vaccine against human immunodeficiency virus (HIV-1), the virus that causes AIDS. In connection with this research, we characterize biochemical and immunological properties of viral envelope glycoprotein, develop and evaluate novel vaccine vectors, and examine virus-host interactions at various levels.
M. Heather Greenlee, Associate Professor, Biomedical Sciences
Systems biology: Combining computational and traditional experimental approaches to understand cell fate determination in the developing retina. Neurodegeneration: Using retinal morphology and function to understand the pathogenesis of prion diseases.
Anumantha Kanthasamy, Distinguished Professor, Eugene and Linda Lloyd Professor, Director of Iowa Center for Neurotoxicology (ICAN), Biomedical Sciences Departmental Chair, Biomedical Sciences
Dr. Kanthasamy's work focuses on the effects of environmental neurotoxicants on pathogenesis of Parkinson's disease and Prion diseases. Interests: neurotoxicology, neuropharmacology, neuroprotection, neuroinflammation, signal transduction, gene expression and regulation, apoptosis.
Central States Society of Toxicology John Doull Award.
Arthi Kanthasamy, Assistant Professor, Biomedical Sciences
Parkinson's disease, stroke and drug abuse. Interests: neurodegeneration, signal transduction, animal models, autophagy, ischemia, apoptosis.
Richard Martin, Professor, M.R.C.V.S., Dip. E.C.V.P.T., Biomedical Sciences
My research activity stems from an interest in the electrical properties of cells and their responses to drugs. I have developed the Ascaris suum, Oesophagostomum dentatum & Schistosoma mansoni preparations for electrophysiological recording and the examination of the mode of action of anthelmintics which exert their effects on membrane ion-channels.
Jonathan Mochel, Associate Professor, Biomedical Sciences
His research, which falls under the scope of the One Health initiative, pertains to the analysis of clinical data obtained from spontaneous animal models of human diseases to bridge the knowledge gap between experimental (i.e rodent) models and patients.
Alan Robertson, Research Associate Professor Biomedical Sciences
Nematode ion channels as anti-parasitic drug targets. Electrophysiology of ligand- and voltage-gated ion channels in nematode parasites and C. elegans. Identifying anti-nematodal modes of action and mechanisms of resistance to anthelmintics. Modulation of ionotropic acetylcholine receptors at the nematode neuromuscular junction. Characterization of novel ion channels and validation as potential drug targets.
Ravindra Singh, Professor and Salsbury Chair, Biomedical Sciences.
Singh group works on the interface of fundamental and translational biology. General interest of his group has been to understand the mechanism of alternative splicing, a vital process that increases the coding potential of genome in all higher eukaryotes. Alternative splicing is also associated with a growing number of diseases including neurological and neuromuscular disorders, cardiovascular disorders and cancer. Particular focus of his group has been to understand the molecular basis of Spinal Muscular Atrophy (SMA), a debilitating genetic disease of infants and children. His award-winning discovery relates to finding a unique regulatory element located within the non-coding region (or intron) of Survival Motor Neuron (SMN) gene. He has termed this novel regulatory element as Intronic Splicing Silencer N1, which is abbreviated as ISS-N1. Currently, his group is working on the mechanistic details of how ISS-N1 could be used as a therapeutic target. His other interests include RNA-protein interactions and isolation of RNA aptamers as detection and diagnostic tools.
Chemical and Biological Engineering
Laura Jarboe, Associate Professor, Chemical and Biological Engineering
Transcriptomic analysis in Escherichia coli; Detoxification of pyrolytic Sugar Syrup for Direct Fermentation of Levoglucosan to Ethanol, Biocatalyst inhibition by carboxylic acids.
Keri Carstens, Collaborator Assistant Professor, Entomology. Environmental Safety Assessment Lead at Pioneer Hi-Bred International Inc. Keri is the Environmental Safety Assessment Lead for Pioneer Hi-Bred. She performs risk assessment research with her team of environmental fate and ecotoxicology scientists to evaluate the safety of Pioneer products in the environment. She received her M.S. and Ph.D. in environmental toxicology from Iowa State University, working under Joel Coats and Tom Moorman. Keri is the President of the Ozark-Prairie Chapter of SETAC.
Joel Coats, Distinguished Professor, Entomology
Joel Coats' major research areas are insecticide toxicology and environmental toxicology. His specific interests in insecticide toxicology include mechanisms of toxic action, selectivity, metabolism, and structure-activity relationships. He conducts studies on the spectrum of activity and mode of action of several classes of natural products as insecticides. Their potential utility in insect control is evaluated, derivatives and analogs are synthesized and bioassayed, and structure-activity relationships are developed.
Food Sciences and Human Nutrition
Aubrey Mendonca, Associate Professor, Food Science and Human Nutrition
Microbial food safety and quality; survival, injury and destruction of foodborne pathogens as influenced by chemical, heat, or irradiation treatment of foods; stress adaptation in foodborne pathogens; detection of pathogens sublethally injured by food processing methods.
Manju Reddy, Professor, Food Science and Human Nutrition
Role of iron in Parkinson's and cardiovascular disease. Cell culture model to assess food iron bioavailablity fo identifying novel enhancing factors and developing new food fortification strategies to reduce the prevalence of anemia.
Kevin Schalinske, Professor, Food Science and Human Nutrition
Nutritional and hormonal regulation of folate/ methyl group metabolism relevant to health and disease. Role of dietary components that affect iron metabolism on preventing these diseases.
Genetics Development and Cell Biology
Jo Anne Powell-Coffman , Professor, GDCB Department Chair, Genetics, Development and Cell Biology
The Powell-Coffman Lab employs a powerful genetic model system, the nematode C. elegans, to study how animals sense and adapt to their environment. Currently, the labs research is focused on two biomedically important transcription factors: the aryl hydrocarbon receptor (AHR) and the hypoxia- inducible factor (HIF).
Natural Resource Ecology and Management
Steven Bradbury, Professor, Natural Resource Ecology and Management
Environmental Toxicology, Pesticide Risk Assessment, Environmental Policy. Dr. Bradbury is contributing to research and extension in University-wide toxicology, environmental, agriculture and natural resource science and policy programs. Areas of emphasis include pesticide resistance management, pollination services, monarch butterfly conservation and sustainable agriculture, including the role of integrated pest management within nested layers of governance. Steve's areas of teaching include toxicology, pesticide and chemical risk assessment and related policy topics.
Dr Jovanovic's main research focus is in the area of Nanotoxicology and Aquatic Ecotoxicology. Primarily he is interested in non-soluble suspended materials of anthropogenic origin - mainly nanoparticles and microplastics and their effects on the environment. He conducts his research in both freshwater and marine environment.
Plant Pathology and Microbiology
Gary Munkvold, Professor and Seed Science Endowed Chair, Plant Pathology
My research program has two foci: diseases that affect the production and utilization of seeds; and epidemiology and management of mycotoxigenic fungi in corn.
Veterinary Diagnostic Lab and Production Animal Medicine (VDPAM)
Wilson Rumbeiha, DVM, Professor, DABT, DABVT, Veterinary Diagnostic and Production Animal Medicine (VDPAM)
Research on Parkinson's Disease.
Veterinary Microbiology and Preventive Medicine
Qijing Zhang, BVsc, Professor and Frank Ramsey Endowed Chair, Associate Dean for Research and Graduate Studies, College of Veterinary Medicine, Veterinary Microbiology and Preventive Medicine
Food safety; antibiotic resistance; bacterial genetics; pathogen-host interactions; prevention and control of infectious diseases. Research in our laboratory focuses on foodborne human pathogen, Campylobacter jejuni. We are using fundamental and contemporary approaches to i) investigate the ecology of Campylobacter in animal reservoirs, ii) examine the molecular mechanisms associated with the development and persistence of antibiotic resistance in Campylobacter and the effect of antibiotic resistance on Campylobacter pathogenesis, iii) define the molecular and cellular mechanisms involved in Campylobacter-host interactions, and iv) develop effective means for the control of Campylobacter infections.